Purified Anti-human CD81 Antibody
Alternate names: TAPA-1 (target of an antiproliferative antibody)
Amount: 50/100 μg
Host: Mouse
Clone: 5A6
Isotype: Mouse IgG1, κ
Clonality: Mouse Monoclonal Unconjugated
Immunogen: Human OCI-LY8 cell line
Purification: Protein A affinity chromatography
Molecular Weight: 26 kDa
Form: Liquid
Formulation: 0.5 mg/ml in Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Species Reactivity: Human
Storage Conditions: at 2-8°C. DO NOT REEZE!
Description: CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8, and CD82 in T cells. CD81 is frequently expressed on exosome membranes used to characterize exosome populations from a variety of body fluids.
Applications
Western Blot:1:250-1:1000
FACS: 1:100
IF:
1:100
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