Anti-ATP1 alpha1/Na+K+ ATPase1 Antibody BES2065LCA
货号 | BES2065LCA |
---|---|
产品名称 | Anti-ATP1 alpha1/Na+K+ ATPase1 Antibody |
基因名 | Atp1a1 |
抗体来源 | Rabbit |
克隆 | Polyclonal |
抗体亚型 | Rabbit |
分子量 | 113KD |
免疫原 | A peptide derived from rat ATP1 alpha1/Na+K+ ATPase1. Immunogen sequence location: 15-64 |
内容 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
纯化方式 | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
浓度 | 500 ug/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
产品形态 | Liquid |
保存条件 | 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
背景资料 | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. |
研究类别 | 1. "Entrez Gene: ATP1A1 ATPase, Na+/K+transporting, alpha 1 polypeptide".2. Dunbar LA, Caplan MJ (2001). "Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.". J. Biol. Chem. 276 (32): 29617–20.3. Xie Z, Cai T (2004). "Na+-K+--ATPase-mediated signal transduction: from protein interaction to cellular function.". Mol. Interv. 3(3): 157–68. |
使用 ATP1 alpha1/Na+K+ ATPase1 Antibody 对 HeLa 细胞裂解物进行蛋白质印迹分析。右边的泳道被合成的肽封闭。