Anti-human CD63 Antibody Biotin Conjugated

Alternate names: LAMP-3; ME491; MLA-1; Granulophysin; Ptgr40; NGA; gp55

Amount: 50/100 μg

Host: Mouse

Isotype: Mouse IgG1, κ

Clonality: Mouse Monoclonal Biotin Conjugated

Immunogen: Human Splenic Adherent Cells

Purification: Protein A affinity chromatography

Molecular Weight: 30-60 kDa

Form: Liquid

Formulation: 0.5 mg/ml in Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide

Species Reactivity: Human

Storage Conditions: Store at 2-8°C. DO NOT FREEZE!

Description: Anti-CD63 recognizes an extracellular fragment of CD63, a 56-kilodalton (kDa), type III lysosomal glycoprotein, belonging to the tetraspanin family. CD63 is expressed by granulocytes, platelets, T-cells, monocytes/macrophages, endothelial cells. CD63 protein is also expressed in exosome membrane. CD63 interacts with integrins and affects phagocytosis and cell migration. CD63 also serves as a T-cell co-stimulator molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 protein is a canonical exosome marker and currently used to characterize exosome populations from a variety of body fluids.

Applications:

ELISA: 1:1000 (Detection)

FACS:

IF: 1:100

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