货号 | BES2312LAb |
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产品名称 | 抗小鼠 CD8a 单克隆抗体 PerCP-Cyanine5.5 偶联,流动验证 |
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基因名 | CD8A |
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抗体来源 | Rat |
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克隆 | Monoclonal |
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抗体亚型 | Rat |
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内容 | Phosphate-buffered aqueous solution, 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
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浓度 | 500 ug/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
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产品形态 | Liquid |
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保存条件 | 12 months from date of receipt, -20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
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背景资料 | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms. |
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研究类别 | 1. Bowcock, A. M., Kavathas, P., Margolskee, R. F., Herzenberg, L., Cavalli-Sforza, L. L. An RFLP associated with pcDLeu2-14, a human T-cell differentiation antigen CD8 (Leu2) cDNA mapped to 2p12. Nucleic Acids Res. 14: 7817 only, 1986. 2. "Entrez Gene: CD8A CD8a molecule" |
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